Silver Sulfadiazine (Topical)

Brand name(s): Silvadene

Proper Use of This Medicine

This medicine should not be used on premature or newborn infants up to 2 months of age, unless otherwise directed by your doctor. It may cause liver problems in these infants.

To use:

• Before applying this medicine, cleanse the affected area(s). Remove dead or burned skin and other debris.
• Wear a sterile glove to apply this medicine. Apply a thin layer (about 1/16 inch) of silver sulfadiazine to the affected area(s). Keep the affected area(s) covered with the medicine at all times.
• If this medicine is rubbed off the affected area(s) by moving around or if it is washed off during bathing, showering, or the use of a whirlpool bath, reapply the medicine.
• After this medicine has been applied, the treated area(s) may be covered with a dressing or left uncovered as desired.

To help clear up your skin and/or burn infection completely, keep using silver sulfadiazine for the full time of treatment. You should keep using this medicine until the burned area has healed or is ready for skin grafting. Do not miss any doses.

Dosing-

The dose of silver sulfadiazine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of silver sulfadiazine. If your dose is different, do not change it unless your doctor tells you to do so.

• For topical dosage form (cream):
  • For burn wound infections:
    • Adults and children 2 months of age and older-Use one or two times a day.
    • Premature and newborn infants up to 2 months of age-Use and dose must be determined by the doctor.

Missed dose-

If you miss a dose of this medicine, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

Storage-

To store this medicine:

• Keep out of the reach of children.
• Store away from heat and direct light.
• Keep the medicine from freezing.
• Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.

Last Revised: 03/17/2000

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