Midodrine (Systemic)

Brand name(s): ProAmatine

Proper Use of This Medicine

The last dose of midodrine should not be taken after the evening meal or less than 3 to 4 hours before bedtime because high blood pressure upon lying down (supine hypertension) can occur, which can cause blurred vision, headaches, and pounding in the ears while lying down after taking this medicine.

Also, midodrine should not be taken if you will be lying down for any length of time.

Dosing-

The dose of midodrine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of midodrine. If your dose is different, do not change it unless your doctor tells you to do so.

The number of tablets that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are taking midodrine.

• For oral dosage form (tablets):
  • Low blood pressure (hypotension):
    • Adults-10 milligrams (mg) three times a day in approximately four-hour intervals during the daytime hours: shortly before or upon rising in the morning, at midday, and in the late afternoon (not later than six p.m.). Your doctor may increase your dose if needed.
    • Children-Use and dose must be determined by your doctor.

Missed dose-

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage-

To store this medicine:

• Keep out of the reach of children.
• Store away from heat and direct light.
• Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
• Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.

Last Revised: 01/30/2001

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