Medroxyprogesterone Injection

Brand name(s): Depo-ProveraŽ
Other name(s): acetoxymethylprogesterone; methylacetoxyprogesterone

Medroxyprogesterone injection may decrease the amount of calcium stored in your bones. The longer you use this medication, the more the amount of calcium in your bones may decrease.The amount of calcium in your bones may not return to normal even after you stop using medroxyprogesterone injection.Loss of calcium from your bones may cause osteoporosis (a condition in which the bones become thin and weak) and may increase the risk that your bones might break at some time in your life, especially after menopause (change of life).The amount of calcium in the bones usually increases during the teenage years. A decrease in bone calcium during this important time of bone strengthening may be especially serious. It is not known whether your risk of developing osteoporosis later in life is greater if you start to use medroxyprogesterone injection when you are a teenager. Tell your doctor if you or anyone in your family has osteoporosis; if you have any other bone disease or anorexia nervosa (an eating disorder); or if you drink a lot of alcohol or smoke a great deal. Tell your doctor if you take any of the following medications: corticosteroids such as dexamethasone (Decadron, Dexone), methylprednisolone (Medrol), and prednisone (Deltasone), or medications for seizures such as carbamazepine (Tegretol), phenytoin (Dilantin), or phenobarbital (Luminal, Solfoton).You should not use medroxyprogesterone injection for a long time (e.g., more than 2 years) unless no other method of birth control is right for you. Your doctor may test your bones to be sure they are not becoming too thin before you continue to use medroxyprogesterone injection.Keep all appointments with your doctor and the laboratory. Your doctor will monitor your health carefully to be sure you do not develop osteoporosis.Talk to your doctor about the risks of using medroxyprogesterone injection to prevent pregnancy.

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