Laxatives (Oral)

Brand name(s): "Agoral "

Proper Use of This Medicine

For safe and effective use of your laxative:

• Follow your doctor's instructions if this laxative was prescribed.
• Follow the manufacturer's package directions if you are treating yourself.

With all kinds of laxatives, at least 6 to 8 glasses (8 ounces each) of liquids should be taken each day. This will help make the stool softer.

For patients taking laxatives containing a bulk-forming ingredient:

• Do not try to swallow in the dry form. Take with liquid.
• To allow bulk-forming laxatives to work properly and to prevent intestinal blockage, it is necessary to drink plenty of fluids during their use. Each dose should be taken in or with a full glass (8 ounces) or more of cold water or fruit juice. This will provide enough liquid for the laxative to work properly. A second glass of water or juice by itself is often recommended with each dose for best effect and to avoid side effects.
• When taking a product that contains only a bulk-forming ingredient, results often may be obtained in 12 hours. However, this may not occur for some individuals until after 2 or 3 days.

For patients taking laxatives containing a stool softener (emollient):

• Liquid forms may be taken in milk or fruit juice to improve flavor.
• When taking a product that contains only a stool softener, results usually occur 1 to 2 days after the first dose. However, this may not occur for some individuals until after 3 to 5 days.

For patients taking laxatives containing a hyperosmotic ingredient:

• Each dose should be taken in or with a full glass (8 ounces) or more of cold water or fruit juice. This will provide enough liquid for the laxative to work properly. A second glass of water or juice by itself is often recommended with each dose for best effect and, in the case of saline laxatives, to prevent you from becoming dehydrated.
• The unpleasant taste produced by some hyperosmotic laxatives may be improved by following each dose with citrus fruit juice or citrus-flavored carbonated beverage.
• Lactulose may not produce laxative results for 24 to 48 hours.
• Polyethylene glycol may not produce laxative results for 2 to 4 days.
• Saline laxatives usually produce results within ½ to 3 hours following a dose. When a larger dose is taken on an empty stomach, the results are quicker. When a smaller dose is taken with food, the results are delayed. Therefore, large doses of saline laxatives are usually not taken late in the day on an empty stomach.

For patients taking laxatives containing mineral oil :

• Mineral oil should not be taken within 2 hours of meals because of possible interference with food digestion and absorption of nutrients and vitamins.
• Mineral oil is usually taken at bedtime (but not while lying down) for convenience and because it requires about 6 to 8 hours to produce results.

For patients taking laxatives containing a stimulant ingredient:

• Stimulant laxatives are usually taken on an empty stomach for rapid effect. Results are slowed if taken with food.
• Many stimulant laxatives (but not castor oil) are often taken at bedtime to produce results the next morning (although some may require 24 hours or more).
• Castor oil is not usually taken late in the day because its results occur within 2 to 6 hours.
• The unpleasant taste of castor oil may be improved by chilling in the refrigerator for at least an hour and then stirring the dose into a full glass of cold orange juice just before it is taken. Also, flavored preparations of castor oil are available.
• Bisacodyl tablets are specially coated to allow them to work properly without causing irritation and/or nausea. To protect this coating, do not chew, crush, or take the tablets within an hour of milk or antacids.

Dosing-

There are a large number of laxative products on the market. The dose of laxatives will be different for different products. The number of capsules or tablets or teaspoonfuls of crystals, gel, granules, liquid, or powder that you use; the number of caramels or wafers that you eat; or the number of pieces of gum that you chew depends on the strength of the medicine. Follow your doctor's orders if this medicine was prescribed, or follow the directions on the box if you are buying this medicine without a prescription.

Storage-

To store this medicine:

• Keep out of the reach of children.
• Store away from heat and direct light.
• Do not store the capsule, tablet, granules, or powder form of this medicine in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down.
• Keep the liquid form of this medicine from freezing.
• Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.

Last Revised: 12/10/2002

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