Factor VIIa (Systemic)

Brand name(s): NovoSeven

Before Using This Medicine

In deciding to use a medicine, the risks of using the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For factor VIIa, the following should be considered:

Allergies-Tell your doctor if you have ever had any unusual or allergic reaction to factor VIIa or to any products that contain mouse, hamster, or cow proteins. Also tell your doctor and pharmacist if you are allergic to any other substances, such as foods, preservatives, or dyes.

Pregnancy-Studies on effects in pregnancy have not been done in humans.

Breast-feeding-It is not known whether factor VIIa passes into breast milk. However, because this medicine may cause serious side effects, breast-feeding is generally not recommended while you are receiving it.

Children-This medicine has been tested in children and no side effects or problems were found that were different from those seen in adults.

Older adults-No information is available about the use of factor VIIa in older adults.

Other medicines-Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking factor VIIa, it is especially important that your doctor and pharmacist know if you are taking any of the following:

• Activated prothrombin complex concentrates (ie, FEIBA, Autoplex T) or
• Prothrombin complex concentrates (ie, AlphaNine, BeneFix)-May increase the risk of side effects

Other medical problems-The presence of medical problems may affect the use of factor VIIa. Make sure to tell your doctor if you have any medical problems, especially:

• Blood clots or a history of medical problems caused by blood clots or
• Heart disease or
• Infection or
• Injury (crush)-These conditions may increase the risk of bleeding

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