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Epoetin Alfa Injection

Epogen ®, Procrit ®<BR>Other name(s): EPO; Erythropoietin Human Glycoform alpha (Recombinant); rHuEPO-alpha Logo

Epogen ®, Procrit ®
Other name(s): EPO; Erythropoietin Human Glycoform alpha (Recombinant); rHuEPO-alpha Logo

Brand name(s): Epogen ®, Procrit ®
Other name(s): EPO; Erythropoietin Human Glycoform alpha (Recombinant); rHuEPO-alpha


What side effects can this medication cause?

Epoetin may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • redness, swelling, stinging, bruising, itching, or a lump at the place where you injected epoetin
  • headache
  • joint or muscle pain
  • upset stomach
  • vomiting
  • indigestion or "heartburn"
  • stomach pain
  • diarrhea
  • constipation
  • runny nose
  • sneezing
  • difficulty falling asleep or staying asleep

Some side effects can be serious. The following symptoms are uncommon, but if you experience any of them, call your doctor immediately:

  • leg pain or swelling
  • shortness of breath
  • coughing up blood
  • cough that doesn't go away
  • blue-grey color or darkening around mouth or nails
  • dizziness
  • fainting
  • blurred vision
  • temporary confusion
  • slow or difficult speech
  • loss of memory or ability to concentrate
  • hallucinating (seeing things or hearing voices that do not exist)
  • extreme tiredness
  • seizures
  • weakness, numbness, heaviness, or tingling in arms or legs
  • floppiness or loss of muscle tone
  • lack of energy
  • increased or rapid heart beat
  • irregular heart beat
  • chest pain or tightness
  • excessive sweating
  • fever, sore throat, chills, cough, and other signs of infection
  • rash
  • hives
  • itching
  • swelling of the face, throat, tongue, lips, eyes, hands, feet, or ankles
  • wheezing
  • difficulty breathing or swallowing
  • hoarseness

You should know epoetin and other erythropoiesis stimulating medications may increase the risk of cardiovascular problems, including death, especially in patients with heart disease. It is important for your doctor to check your hemoglobin while you are taking epoetin. If your hemoglobin rises too high or too fast while using epoetin, serious problems may occur, including edema (swelling of the hands, feet, ankles, or lower legs), heart attack or heart failure, high blood pressure, seizures, stroke, and blood clots in your heart, legs, or lungs. This increased risk for high blood pressure, seizures, and blood clots reported with epoetin appears to be less in people with HIV using zidovudine and epoetin, and less in people with cancer using epoetin, than in people with serious kidney disease using epoetin. Talk to your doctor about the risks of using epoetin.

Epoetin may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

Last Revised: 01/01/2005

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