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Epinephrine Injection

Epipen; Epipen Jr. Logo

Epipen; Epipen Jr. Logo

Brand name(s): Epipen; Epipen Jr.


How should this medicine be used?

Epinephrine injection comes as a single-dose pre-filled automatic injection device to be injected into the thigh. You should only use it when you are experiencing or are likely to begin experiencing a serious allergic reaction. Talk to your doctor about substances that may cause serious allergic reactions and symptoms of these reactions.

Under certain conditions, you may need more than one epinephrine injection to treat an allergic reaction. Your doctor will tell you if and when you should use a second dose. Follow the directions on your prescription label carefully and ask your doctor or pharmacist to explain any part you do not understand. Use epinephrine injection exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

To use the automatic injection device, follow these steps:

  • Hold the device firmly in your fist with the black tip pointing down. Do not touch the black tip; hold only the cylinder.
  • Remove the gray activation cap.
  • Move your hand so the black tip is near your outer thigh.
  • Swing your hand away from your body, then jab the black tip firmly into your outer thigh at a 90-degree angle. You may inject the needle through clothing that is covering your thigh.
  • Keep the device firmly in this position for several seconds.
  • Remove the device from your thigh and rub the area with your fingers.
  • Look at the black tip to see if the needle is showing. If the needle is not showing, repeat steps 3-6.
  • If the needle is showing, you have received the full dose of epinephrine. You will notice that most of the liquid remains in the device. This is extra liquid that cannot be used.
  • Press the needle against a hard surface.
  • Replace the device in the carrying tube (without the activation cap) and cover with the cap.

After you use the automatic injection device, follow these steps:

  • If you were stung by an insect, try to remove the stinger with your fingernails. Be careful not to push the stinger deeper into the skin and not to pinch or squeeze the area. If you can, put ice and/or baking soda soaks on the area.
  • Go to the nearest hospital emergency room right away. Take the used injection device with you. Tell the doctor that you have used the device and give it to him for disposal.
  • Rest and avoid physical activity as directed by your doctor.

Handle the automatic injection device carefully to avoid accidentally injecting the epinephrine into your hands. If you do accidentally inject the epinephrine into any part of your body except your thigh, go to the nearest emergency room right away.

Last Revised: 04/01/2003

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